Bello slim Gel is a highly effective combination of fat burning actives for a topical treatment of thighs, buttocks, hips, waist and arms.
The active substances are caffeine and synephrine. Synephrine is a highly active compound isolated from bitter orange (Citrus aurantium), that was first used by body builders as a fat loss stimulant and to increase the metabolic rate.
Both ingredients activate the breakdown of lipids in fat cells of the adipose tissue. To enhance the penetration into deeper skin layers, caffeine and synephrine are enclosed in liposomes.
Biochemistry of the fat breakdown
Neutral fat (triglycerides) is stored in fat layers, also called adipose tissue. The metabolism of fat is regulated by hormones. The hormone epinephrine (adrenaline) is the initiator of the breakdown of neutral fat. It leads to the release of free fatty acids from the adipose tissue into the blood system.
Epinephrine binds to the adrenergic receptor on the surface of fat cells. Binding leads to the production of the second messenger cAMP inside the fat cell. The messenger cAMP activates the enzyme lipase that cleaves neutral fat into free fatty acids and glycerol. Free fatty acids are then transported into the blood system and used to generate energy.
Synephrine, a substance found in bitter orange, is similar to epinephrine. It can therefore also bind to the adrenergic receptor and initiate the release of fatty acids. Synephrine as food supplement has become very popular in bodybuilding and fitness clubs. It is used to stimulate fat burning and therefore contouring the body.
Caffeine is a very traditional ingredient to stimulate fat breakdown. Caffeine inhibits the activity of phosphodiesterase, the enzyme that normally leads to the breakdown of the messenger cAMP. Caffeine increases therefore the half-life of cAMP, the activator of the lipase enzyme.
Synephrine initiates the release of fatty acids and
Caffeine increases the breakdown of neutral lipids in the adipose tissue.
Genistein is the most abundant isoflavone in soybeans
Bello Slim Gel is a highly effective combination of fat burnig ingredients for topical treatments of all body parts you feel concerned about.
Bello Slim refines and firms body contours with longlasting results Your body's contours are beautifully re-contoured for a more slender figure.Bello Slim Contour Control an innovative double targeted body shaping treatment Helps you to obtain a more refined shape Reinforced firming action
The thermogenic formula prevents the appearance of body fat and by its firming properties helps restore the body's smooth contour Bello Slim shapes, firms and contours while it leaves the skin with a silky touch Reshaping Body Moisturizer with an immediate and efficient skin tightening effect for visible firmer skin
Each gram of gel prepared with 2.5% w/v. of the following herbal extracts :
Camellia sinensis extract (Tea, Caffeine), Aloe barbadensis extract (Kumari), Ocimum sanctum extract (Tulasi), Anethum sowa extract (Soya been) in a perfumed gel base.
HOW TO USE :
Wash the area where fat is more and apply Bello Slim gel and rub gently. Do twice or thrice a day.
FOR EXTERNAL USE ONLY
100 gms with Tube Pack.
Literature & Clinical studies of active ingredient of Bello Slim Gel can be sent upon request.